Progesterone in sesame oil vs ethyl oleate


In the rare cases that conttonseed oil causes an allergic reaction, olive oil or ethyl oleate is used. the second IVF cycle i used progesterone in ethyl oleate. In the current study we used estradiol benzoate, progesterone, and a placebo of refined sesame oil, while Itsekson et al. Just know that they are worth it! Oils Soyabeen oil, sesame oil, isopropyl myristate, ethyl oleate, ethyl laurate, labrafil M, campul TABLE 2 Overview of nasal microemulsion. Progesterone in sesame oil 50 mg/ml 10 ml vial qty Progesterone in ethyl oleate 50 mg/ml 10 ml vial qty Progesterone suppositories mg qty Sig: (= days) refills Draw: 3cc 18G 1½” syringe/needles qty Inject: 22G 1½” needles qty Mass. Experimental Example 3 Coconut oil is a MCT oil as is palm kernel oil. Follow me in the next couple of posts as I explain the good, the bad, and the ugly. PROGESTERONE INJECTION . I became crippled on the PIO in sesame oil, truly, as in could not walk at all. Safety container. I suppose the completely clear medium viscosity steroid carrier oil is refined from these raws. I read on another blog that progesterone in ethyl oleate is still available, just the sesame oil (and maybe also peanut?) is in short supply. Ethyl Oleate: Thinnest compound for IM injection. . illustrate the longer term 803726 Progesterone USP (Y5) Micronize 10 G 14K12-U03-021723 05/10/19 $ 10. I am not sure why she is concerned about this, I told her I should be fine with sesame oil, but she felt I should use a different medication. If you've been following along exceptionally closely, and have a memory like a steel trap, you might say, "Wait, why did you switch progesterone oil types?" Well, let me tell you. You get bottles of PIO (or Progesterone in Oil) that a pharmacy compounds for you. , vitamin K, vitamin E) preparations. Be that as it may, our favourite form of progesterone, taken by less than 10 per cent of IVF patients, is the intramuscular injection (Gestone, Prontogest, Agolutin). Note: Your physician may instruct you to use the same needle that you will be drawing It could be in peanut, sesame, cotton, olive, and ethyl oleate. If you are a patient with allergies we can produce Progesterone in various forms – sesame oil, olive oil, ethyl oleate, and 17-hydroxy. Sesame Oil Olive Oil Ethyl Oleate Sig: Inject 1ml (50mg) IM QD UD Refill _____ times PROMETRIUM 100 mg 200 mg # _____ Caps Sig: Use vaginally or orally 1-3 times a day UD by MD Refill _____ times CRINONE 8% # _____ Prefilled Applicators Ethyl Oleate Ethyl Oleate Ethyl Oleate Ethyl Oleate Ethyl Oleate Ethyl Oleate Ethyl Oleate Ethyl Oleate I cannot stress it enough. glycerides peanut oil, corn oil, soybean oil, sesame oil, olive Progesterone is a water-insoluble steroid and is solubi- Ethyl alcohol 20%. The experimental results show that each of ethyl oleate, ethyl benzoate, glycerol triacetate, and castor oil is miscible with ethyl lactate; the mixture of castor oil with one of ethyl oleate, ethyl benzoate, glycerol triacetate, sesame oil, olive oil, corn oil and soybean oil is miscible with ethyl lactate. I haven't tried it yet because I am not that far along in my cycle! The PIO in ethyl oleate that I have gotten is compounded at 100mg/mL so in addition to being thinner the dosage was 1/2 as much as sesame. , progesterone, testosterone) and vitamin (e. This is oil tends to be a thinner compound than the olive oil blend. 00 296. You will be injecting 2cc/ml once daily. It wasn't large hives, rather the bumps were smaller and all over. Progesterone with ethyl oleate is what my RE gave me to use. The suspension is not a food-based oil and she feels there's a lower risk of it containing gluten. 25 ml sesame oil <----- using 36. The nurse at the clinic did the very first shot, and she showed DH where to put it and how to do it. I really disliked suppositories, but the injections had me wishing for them. Progesterone is given by intramuscular injection. The last couple of times I did progesterone in ethyl oleate and I didn't have any problems. She is recommending something called Ethyl Oleate Progesterone. Progesterone in oil is given as an intramuscular injection in the upper buttocks, near the hip. Is anyone else having to take the progesterone injections? There’s a national shortage of progesterone in oil so they have switched me to progesterone in ethyl oleate. If you have any allergies to peanuts or sesame, make sure to mention it to your doctor so he can prescribe progesterone in olive oil instead. Massachusetts pharmacy issues fertility drug recall When someone is sick, they put their trust in pharmaceutical companies to provide safe and effective medications for their treatment. It’s the same progesterone, it’s just suspended in a different type of oil. It changed everything for me. This medication is an inter-muscular injection (just like it sounds, the needle goes into the muscle). 87 Progesterone Ethyl Oleate 50mg/ml 10ml $67. 5 per cent and did not differ significantly from each other. 25ml Oil. What worked for me was; injecting with 25 g needles (which you should have for the ethyl oleate), pushing the needle in slow worked for me, but Progesterone In Oil Shortage December 6, 2017 December 6, 2017 MommySquared I was fortunate to start this cycle with 2. Sesame Oil. The influence of estradiol on cholesterol processing by the corpus luteum Article (PDF Available) in Biology of Reproduction 40(5):961-71 · June 1989 with 13 Reads How we measure 'reads' Progesterone in oil Progesterone in oil (50mg/ml) intramuscular injections will begin the day after the IVF egg retrieval or the day after the IUI. The progesterone in ethyl oleate is the least allergic medium for the progesterone to be mixed with. You can use a 50/50 concentration of Ethyl Oleate and oil such as Cottonseed or Grapeseed to increase concentration of NPP to 200mg/ml without crashing Some people feel that isn't all that it is cracked up to be as many long ester formula's seem to crash. Hi all, not really sure where to post this to get the most views, but here goes! I had a terrible reaction to the progesterone in sesame oil my last FET cycle and my Dr is trying to call in a prescription for progesterone in ethyl oleate and I cannot find a pharmacy to fill it! Progesterone injections (50 mg or 1 ml of progesterone in oil) are commonly given after egg retrieval during an IVF cycle. While leading drug manufacturers like Teva, West Ward, and Fresenius Kabi combine progesterone with sesame oil, some specialty or compounding pharmacies create made-to-order progesterone injections with ethyl oleate or olive oil (this is often done when a patient is allergic or has unwanted side effects with sesame oil). compounding pharmacy recalls progesterone and other fertility drugs. g. The severe pain associated with prop post injection is a crash “in depot”. 2016-04-24 2017-02-08 peptidesteroid Single Steroid Injectable The benefits of using our oral liquid products: The compound will bypass and NOT intoxicate the liver. Progesterone injection is available in generic form. If you can, see if you can get the progesterone in ethyl oleate oil vs. Endometrin * what is your thoughts. Sher Fertility Institute 146,825 views Ethyl oleate. 2) the oil the P4 is suspended in: My Rx is for P4 in ethyl oleate, which is decently thin. Some of the solutions contained more than 10% progesterone. 1) Antibacterial Agents: Both vaginal Vs I. As for oil progesterone form, it can be assigned as a part of the mixture of other carrier oils, because some people have allergic reactions to progesterone, so it has to be mixed with other oils: peanut oil, ethyl oleate, olive oil, cottonseed oil, sesame oil and so on. The PIO in ethyl oleate is not as thick as the others. These involved a long needle that was used to deliver the medication in the buttocks. I did the heating the oil, smaller needle, warming before and after where I gave the shot, massage, all -----corn oil, cottonseed oil, peanut oil, and sesame oil-Fixed oils are used as vehicles for certain hormone (e. On occasion, Dr. Progesterone is usually compounded in sesame oil. The addition of ethyl oleate to sesame oil can effect small changes in the pharmacokinetic profile, the effect being generally beneficial with respect to persistent efficacy when the ratio of sesame oil/ethyl oleate is 90:10 v/v. I've tried PIO in sesame oil and ethyl oleate, and everyone said the EO would be easier, but it really wasn't for me (it burned, caused bigger lumps and bruises). The Type II formulations, defined as SEDDS, are isotropic mixtures of lipids and lipophilic surfactants (HLB < 12) that self‐emulsify to form crude oil‐in‐water emulsions when introduced in aqueous media. Eventually I begged to be switched to another type of PIO and was given progesterone in olive oil, which cleared up all the previous pain and after a few weeks, SGF tends to prescribe sesame oil - but there is a nationwide shortage now so most people are on ethyl oleate. Pharmacy stated the vials have a hard shelf life of 30 Valproic acid has been formulated as an oil solution but, other than that, oil solution dosage forms are primarily known from fat soluble vitamins; vitamin A, D and E are often dosed in oil. Some people experience a reaction when a particular carrier oil is used, and will need a different oil base prescribed. It has ester value between 95 – 105%. 21 Sep 2007 11, 59, 60 with ethyl oleate as oil, soybean lecithin (Epikuron 200) as amphiphile of sesame and saffola containing systems decreased with the rate of shear. then heating pad for 10 minutes afterwards. 17ml Ethyl Oleate . Ethyl oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. Not tested on animals. This is the BAD LIST of what to avoid in your skin care products. Refill _____ times On day 14, I started progesterone intramuscular shots (this time in ethyl oleate, not sesame oil), and tonight, I added in the blood thinner (Lovenox). This is a big deal because it is traditionally manufactured and suspended in sesame oil, but that fucking sucks because it’s thick and requires a thick-ass needle. Progesterone in Sesame Oil In: Finding a Resolution for Infertility. Progesterone Ethyl Oleate vs. This post lists comedogenic ingredients and products containing those ingredients above a certain threshold. The test might well then produce a different color pattern than what their chart says. This is a very effective treatment but can be painful with time as the “oil” tends to accumulate, it is thick and difficult to inject intramuscularly (usually requires a 1. Occasionally it can be given orally bit is considered less effective. Sterile gauze. Pharmacy stated the vials have a hard shelf life of 30 Progesterone is generally prescribed in 2 forms -- injection and vaginal. The liquid is thicker (more viscous) than the other medications because it is in an oil solution (sesame oil, cotton seed oil, and ethyl oleate are common carriers for the progesterone). This medicine may stop you from having a period (menstrual bleeding) for some time. The Winstrol will kick in at a faster rate, oppose to tablet. One needle for drawing up the medication. However, it is not unheard of for dangerous and defective drugs to reach unsuspecting consumers. Drug Name of ingredient Comment References Diazepam S- tween 80 O- ethyl laurate,ettyl oleate Cos- propylene glycol, ethanol ME system be a promising approach for the PIO – we are going with progesterone in sesame oil instead of ethyl oleate …we have done both. pharmacies as a vehicle for intramuscular drug delivery, in some cases to prepare the daily doses of progesterone in support of pregnancy. When referring to the below chart on the melting point of fats, keep in mind that melting temperature is the same as freezing temperature; it's the temperature where the fat transitions from a liquid to a solid. Also heat more oil than you need, as you will not be able to get it all out of the pan. Ethyl oleate was by far the easier for me. With the shots, the progesterone is going directly into the blood and can be measured in the blood. It was hard to find a pharmacy that made it, but I  I use freedom, and my PIO is suspended in sesame oil. My hips are so sore and stiff from the injections. The sterots are removed completely by the first 15 ml of n-heptane. The Progesterone can come in all types of oil from Extra Virgin Olive Oil to Sesame Oil. -The label must state the name of the vehicle, so the user may be aware in case of known sensitivity or other reactions to it. PROGESTERONE IN OIL $84. Have people had successful pregnancies with ethyl oleate? I had a rash all over my back early on. It is given as a supplement to thicken the uterine lining and prepare the body to store the embryo. There are three other oil available to use in progesterone injections if the patient is allergic to both sesame and peanut oils. Donahue may prescribe a different dose such as only taking 1cc/ml daily if someone is going through an injectable cycle with an IUI. -----corn oil, cottonseed oil, peanut oil, and sesame oil-Fixed oils are used as vehicles for certain hormone (e. Might be worth checking on. Peanut oil alone gave 89 per cent of nonspecific reactions mostly of an allergic type (pruritis). I switched to Sesame Oil and had no problems. 4. This is not a method of birth control. So the new oil is thinner and doesn’t require as thick a needle. Ethyl oleate is made to reduce pain in injection. that made the shot less painful and the liquid dispersed more easily under the skin. Progesterone Injection. The following list contains more than 8000 terms which an expert in biology and chemistry has checked manually and evaluated as salicylate-free or salicylate-containing. i iced for 15 minutes ahead of time. Progesterone Injection Sesame Oil 50 mg/ml, 100 mg/ml. 17ml Grapeseed Oil. slope of the plot of log Sm vs. Top 10 Facts About Vaginal Progesterone and Assisted Reproductive Technologies. Or in my case PEO, as I have Progesterone in Ethyl Oleate. B: Gonal F 3 00IU Pen 450IU Pen 900IU Pen 75IU 450IU M -D 10 50IU M -D _____ Re ills The progesterone steroid (figure 1) is not water-soluble. The sesame was considerably cheaper but I am willing to pay extra to avoid the discomfort I had with sesame. The most common oils used to do this are ethyl oleate, olive oil, sesame oil, or peanut or cottonseed oils, as Growing Nowadays, seems like everyone is using UG labs or “homebrew”. Hydroxyprogesterone Caproate Injectable, Progesterone in Ethyl Oleate Injectable, and Progesterone in Sesame Oil Injectable drug products are labeled for injection and must meet the compendial Progesterone injection or suppositories? - posted in IVF/FET/IUI Cycle Buddies: I'm not sure where to ask thisbut I am given the option of either doing progesterone muscular injections or progesterone suppositories starting on the day of my egg retrieval. Progesterone is also used to treat abnormal bleeding from the uterus that is due to low hormone levels and not other causes (e. When this sort of solution interacts with water in the tissues, it causes the progesterone to crystallize out of solution. 00 FedEx Next Day Delivery (Most Shipments) NO CHARGE Sharps Container (Most Shipments) NO CHARGE Women needing the aid during the first trimester of pregnancy are often prescribed intramuscular injections which are typically made by mixing progesterone with one of the following oils: Ethyl Oleate, Olive Oil, Sesame Oil, Peanut and Cottonseed Oils. Alcohol swabs. My RE changed me to progesterone in ethyl oleate. Preparing and Administering Progesterone In Oil. The kinds of oil used are sesame, cottonseed, peanut, olive, and ethyl oleate. Sustanon Related Best Hot Sale Anabolic Steroids: Methenolone Enanthate vs Methenolone Acetate – Best Cutting Steroid Both Methenolone Enanthate (303-42-4) and Methenolone Acetate (434-05-9) constitutes of How to Take Anastrozole 1985 No. It is believed that Winstrol helps block the progesterone buildup while the Deca heIps with the joint issues that some suffer while on Winstrol. Refill _____ times Fertility Medication Recall Hits Michigan. I eventually got discomfort with the ethyl oleate but it took a lot longer than the sesame. , Subcutaneous aqueous versus vaginal progesterone gel for luteal phase support in intrauterine  19 Oct 2017 It is much thicker when compared to ethyl oleate and this means that it Progesterone is available in both sesame oil and even in ethyl oleate. It’s almost nerve damage-like stinging. The peanut and sesame oil commonly does cause swelling. e. In the form of injection , progesterone is generally mixed with some form of oil -- think cooking types of oil-- sesame oil, cottonseed, ethyl oleate, and peanut oils. Or your supplier used different amounts of benzyl alcohol or benzyl benzoate than their product used. 40 805762 Pyridoxal-5-Phosphate Monohydr 5 G 17K30-U03-042958 07/07/19 $ 24. This "thick" oil is necessary to make the hormone progesterone injectable. The final separation of the testoster- one propionate from the sterols and triterpenoids of the oil, as well as free testosterone, is achieved with the Celite- nitromethane column, using n-heptane as mobile phase. I was given a full vial of P4 in sesame oil that was so thick drawing it took  Progesterone in Ethyl Oleate/Progesterone in Sesame Oil. Progesterone lozenges (made by pharmacist to order); Oral tablets (Prometrium, but it also can be used vaginally). The problem is, it's not readily available. Supp. Progesterone in sesame oil, olive oil, ethyl oleate; progesterone suppositories; Crinone – I’ve been on it all and had plenty of the little disasters that accompany them. Progesterone, a Look at the Oils. IVF Medication Injections - Progesterone in Oil - Duration: 7:25. 50 mg/ml 10 ml Vial # _____ Vials Sesame Oil Olive Oil Ethyl Oleate Sig: Inject 1ml (50mg) IM QD UD. 5-inch needle). All Strengths (Each) $1. I was given the ethyl oleate from the start, but if I get good news this week I’ll definitely check on refill supplies to make sure that’s true. It’s a thin and expensive oil, created from ethanol, and used as a rubber softener, solvent, and typically used by us as a base for steroid solutions. While it is thicker than ethyl oleate, thus requiring a thicker needle, many women report that this blend offers some of the easiest absorption into the muscle. Try the shot again and if it still bothers you ask if you can switch the type of oil the progesterone is in. 24 ml of sesame oil 24 ml of grapeseed oil My Duvia would be, which of the above ingredients should I substituted by ethyl oleate? 50% you speak, would look like? : 100ml 48 ml ethyl oleate 2 ml benzyl alcohol 30 ml of testosterone enanthate 10 ml of sesame oil 10 ml grape seed oil my reasoning this right ? Progesterone is usually compounded in sesame oil. Supposedly the ethyl oleate works better because it's thinner and leaves more of a bump. My IUI and first IVF cycle i used progesterone is sesame oil. That stuff BURNED, though and made me sore all day. Refined sesame oil was used as a control because it was the vehicle in *Progesterone in oil can also come in a variety of carrier oils. For me, the ethyl oleate really stings. The vehicle used for dissolving the progesterone consisted of benzyl alcohol, ethanol, and ethyl oleate. My question is this, is it just as effective as PIO in sesame oil? If it's not, I'd just assume stick with what I've always used. 80 804386 Progesterone, Wettable, Powder 100 G 14I05-U18-020888 07/23/19 $ 89. 45 Sesame oil 0. 5. Doing so many cycles, it might just be a matter of changing it up from time to time. Also, P only dissolves in oil (peanut, olive, ethyl-oleate etc) and repeated injections were painful and sometimes resulted in sterile abscesses. Capsules All Strengths (Each) $1. And since I stopped the suppositories temporarily and the hives continued, I know it's not them this time. In fact, I had a severe allergic reaction to the sesame oil. 00 EO = Ethyl Oleate. If you are 65 or older, use progesterone injection with care. Instead, you could try an injectable progesterone made with an oil other than sesame oil so that would be one option, or a pharmaceutical formulated progesterone such as Crinone 8% or Endometrin would be alternatives. The oil that holds the progesterone can make the shots uncomfortable. , Hisar(Haryana), India b Department of Pharmaceutical Sciences,M D University, Rohtak(Haryana), India Progesterone in oil Progesterone in oil (50mg/ml) intramuscular injections will begin the day after the IVF egg retrieval or the day after the IUI. Progesterone Injection Ethyl Oleate 50 mg/ml, 100 mg/ml. One long needle for administration. You might also get yours compounded in olive oil or sesame oil. , Hisar(Haryana), India b Department of Pharmaceutical Sciences,M D University, Rohtak(Haryana), India Is your progesterone in oil the ethyl oleate or something else like sesame or olive oil? How does it compare to the ethyl oleate? Crinone vs. Self Emulsifying Drug Delivery System: A Tool in Solubility Enhancement of Poorly Soluble Drugs Kavita Sapraa*, Ashu Saprab, S K Singha, Saloni Kakkarb a Department of Pharmaceutical Sciences, G J University of Science & Tech. Shop online with confidence, fast free secure shipping available Instead, you could try an injectable progesterone made with an oil other than sesame oil so that would be one option, or a pharmaceutical formulated progesterone such as Crinone 8% or Endometrin would be alternatives. Progesterone in oil (PIO) is natural progesterone suspended in oil and administered as an intramuscular injection. (For Ethyl Oleate add $10) anyone that has experience with test prop conversions please chime in for me here i have heard lots of people saying test prop with ethyl oleate is pretty much painless well I have got my hands on some ethyl oleate and was wondering if this formula would still be the same for making prop with ethyl oleate instead of sesame oil 5 grams powder 36. The substance crystalizes in the injection site due to improper solvent ratios. Parenteral Added Substances. 296. UR- Sesame oil meets the standards of Ph. it was thinner and i was able to use a smaller gauge needle with it. Busyblossom - stim cycles A new progesterone formulation that is less viscous and easier to inject is now available in the US (requires compounding) which uses Ethyl Oleate as the base rather than peanut, cottonseed or sesame oil. Olive oil, sesame oil, and ethyl oleate produced a lower percentage of nonspecific reactions, particularly of the orthoergic type (simple erythema). I've been on Progesterone shots for four days now. 58 Castor oil 20 Miglyol 810 3. Ethyl oleate is produced by the body during ethanol intoxication. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. Superiority of one over the other has not been established. EO = Ethyl Oleate. Basically using Ethyl oleate makes the injection smoother and painless for example if you need 100ml oil. very thick. Because HCG use is likely to increase the chances of OHSS , and theoretically hyper stimulation can occur only with clomiphene also , progesterone is the preferred drug for luteal support in All kinds Oils for Injectable Steroid Oils. Deca can be used for cutting or for bulking. 00 - 3. 4 grams Methenolone enanthate. I am allergic to sesame so I had ethyl oleate. It has some pretty gnarly side effects. A type of pneumonia has happened with progesterone Progesterone injections are usually continued until 10-12 weeks of pregnancy. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. 2ML Progesterone is a hormone that supports pregnancy and it is compounded in different solutions to accommodate patients’ various needs. It had been found that some people don't absorb the progesterone from suppositories. I think try one and if it bothers you switch it up. If this occurs, cottonseed, olive, or ethyl oleate oils are used instead. I was also fine with cottonseed oil, which is a little thinner than sesame oil. Progesterone 50 mg/mL (Prontogest, in ethyl oleate with benzyl alcohol; IBSA Farmaceutici Italia, Lodi, Italy) was tested as previously described 2: intracutaneous injection of 1/100 diluted - sesame oil - soybean oil (source of fat in IntralipidR) - ethyl oleate - isopropyl myristate. My FET is The best is ethyl oleate which is much thinner so easier to draw up and inject- my progesterone levels were the same on both sesame sees and ethyl oleate, so if given a choice, I would do the PEO. So I’m prescribed progesterone suspended in ethyl oleate. I have several bottles of the PEO left and I'm not about to ask R&T to pay for more meds for just three more weeks. M route have been considered adequate. The deca / winstrol stack is also very popular. February 25, 2013 at 7:49 pm • Progesterone Injection Sesame Oil 50 MG/ML, 100 MG/ML • Progesterone Injection Ethyl Oleate 50 MG/ML, 100 MG/ML PROGESTERONE INJECTION 50 mg/ml 10 ml Vial # _____ Vials Sesame Oil Olive Oil Ethyl Oleate FERTILITY REFERRAL FORM Today’s Date Oils Soyabeen oil, sesame oil, isopropyl myristate, ethyl oleate, ethyl laurate, labrafil M, campul TABLE 2 Overview of nasal microemulsion. Please stick to answers based on facts and your own experiences as you respond, and keep in mind that your contribution will likely help people who don't actually know anything else about you (so it might Progesterone injection or suppositories? - posted in IVF/FET/IUI Cycle Buddies: I'm not sure where to ask thisbut I am given the option of either doing progesterone muscular injections or progesterone suppositories starting on the day of my egg retrieval. Progesterone is available in both sesame oil and even in ethyl oleate. Symptoms were worse on injections, not to mention that the injections hurt like h311!! I even did progesterone in etheyl oleate (instead of thicker progesterone in sesame oil), and my butt was sore for months and could barely walk at times. Good luck! I have always used 25g needles, but am looking forward to a much easier injection. Also the other con is the cost of Ethyl Oleate. 100 mg/ml in Sesame Oil, 10 ml vial. Detail: 500ml @ Anomass 400mg. Figure 2 illustrates this separation. Do not use any other vaginal products when receiving treatment with vaginal progesterone, as they may interfere with the absorption of progesterone. Featured Post buy best pure pre-made steroids oils testosterone acetate online Leave a comment Ethyl Oleate (Pharma grade) Ethyl Oleate EP / USP – Oleic Acid Ethyl Ester Ethyl Oleate EP/USP is a pharma grade ester formed by the condensation of the fatty acid, oleic acid and ethanol. This time round I went to a compounding pharmacy and got the progesterone in olive oil. check if you can try a different oil. Perhaps your supplier used ethyl oleate while their product happened to use, say, sesame oil. The most common oils used to do this are ethyl oleate, olive oil, sesame oil, or peanut or cottonseed oils, as Growing Try to find a prop with less benzyl alcohol, more benzyl benzoate and better yet, ethyl oleate as the carrier vs sesame oil. Answers. It is used for patients with peanut allergies or those who have had a previous reaction to the progesterone in sesame oil. Village Fertility Pharmacy said that only 5 percent of its overall business comes from compounded products. On day 14, I started progesterone intramuscular shots (this time in ethyl oleate, not sesame oil), and tonight, I added in the blood thinner (Lovenox). in IPM/AOT/water, compared to the aqueous solution of the drug. Progesterone injections are usually continued until 10-12 weeks of pregnancy. You use the needle to the right. Sesame oil and ethyl oleate parenteral oil formulations allow doramectin to express high therapeutic and persistent efficacy, are convenient to administer and well tolerated at the injection site. One multiple dose vial of Progesterone in Oil 10ml/10cc. This has been available in Europe for several years. If you are currently taking progesterone injections and finding it difficult, the following tips can help simplify the process. Currently we see carrier oils such as: olive oil, peanut oil, cottonseed oil, sesame oil, and ethyl oleate. Mine were compounded in Ethyl Oleate which is apparently the most fluid of the oil compounds. my bumps and bruises weren't so bad. Progesterone is used to mimic pregnancy in the body and sustain a viable early pregnancy. Progesterone in Sesame Oil - posted in IVF/FET/IUI Cycle Buddies: Does anyone have any experience progesterone in sesame oil? I normally buy my PIO from my clinic but its 8 hours away so I have to have it compounded in a pharmacy in Vancouver and shipped up to where I live. Leuprolide suppresses natural ovulation. Olive Oil – Olive oil is also commonly compounded with progesterone. Due to its hydrophobic characteristics, progesterone has not been available until now for subcutaneous or even intravenous administration. Refill _____ times 30. The nurse at my clinic suggested that I try Progesterone in Ethyl Oleate as it is easier to inject and people seem to have less issues with it. or sesame oil or ethyl oleate). Common forms are vaginal suppositories (Endometrin) and intramuscular injections compounded with oil (Ethyl Oleate, Sesame Oil, or Olive Oil are common. My doc thought I might have a mild allergy to the sesame oil it was in. Allergic reaction is possible to sesame and peanut oil. These percentages varied between 15 and 31. Unfortunately Olive oil can be quite problematic for acne prone skin but that doesn’t mean you have to run for the hills when you see the word Olive in the ingredients list. EO is a solvent, which dissolves the powder but its use is to thin the solution’s viscosity. Ethyl oleate is thinner apparently so slightly easier to inject - but I've been on cycles with both and I have the same reaction to both. as the hydrophilic phase. Progesterone is mixed with different oils for intramuscular (in the muscle - IM) injection: Olive Oil: Creates a thick consistency requiring a thicker needle – believed to provide easiest muscle absorption of all compounded progesterone options. We tend to order progesterone in ethyl oleate for our patients. I even have a whole routine of warming the oil, then massaging it in, then sitting on a 2) the oil the P4 is suspended in: My Rx is for P4 in ethyl oleate, which is decently thin. 5 bottles of PIO from our last cycle, and I am slowly making my way down to one bottle so I decided to call in a refill to a nearby-ish fertility pharmacy. The optimal route of progesterone administration is not yet known. Have people had successful pregnancies with ethyl oleate? Progesterone In Ethyl Oleate. 5 ml sesame oil. Women needing the aid during the first trimester of pregnancy are often prescribed intramuscular injections which are typically made by mixing progesterone with one of the following oils: Ethyl Oleate, Olive Oil, Sesame Oil, Peanut and Cottonseed Oils. One syringe. The most common oils used to do this are ethyl oleate, olive oil, sesame oil, or peanut or cottonseed oils, as Growing As for oil progesterone form, it can be assigned as a part of the mixture of other carrier oils, because some people have allergic reactions to progesterone, so it has to be mixed with other oils: peanut oil, ethyl oleate, olive oil, cottonseed oil, sesame oil and so on. Progesterone– Most surrogates will be on progesterone for many weeks. I wish I could be more help. Talk with the doctor. 72 Ethyl oleate   The placenta will make both estradiol and progesterone after Week 10-12. 28 Venturella R et al. meanwhile,if u wouldn’t like to use Ethyl Oleate or Grape seed oils to make injectables,the Safflower oil, Sesame oil,MCT oils still could be replaced surely. Chemical and thermochemical aspects of the ozonolysis of ethyl oleate: Decomposition enthalpy of ethyl oleate ozonide Article in Chemistry and Physics of Lipids 175-176 · August 2013 with 76 Reads Comedogenic: Tending to produce or aggravate acne. Progesterone in sesame oil 50 mg/ml 10 ml vial qty Progesterone in ethyl oleate 50 mg/ml 10 ml vial qty Progesterone suppositories mg qty Sig: (= days) refills Draw: 3cc 18G 1½” syringe/needles qty Inject: 22G 1½” needles qty Sig. Progesterone Injection Olive Oil 50 MG/ML, 100 MG/ML Progesterone Injection Sesame Oil 50 MG/ML, 100 MG/ML Progesterone Injection Ethyl Oleate 50 MG/ML, 100 MG/ML Progesterone in Sesame Oil 50mg/ml 10ml $39. It is typically dispensed in a more concentrated dose than the progesterone in sesame oil. I believe the ethyl oleate might get absorbed faster since it is not oil base, but the pharmacist has to make it on site so it is about $30 more per bottle. . The oil could be grape seed oil, or sesame oil, coconut oil with part of ethyl oleate, MCT. a synthetic preparation of the caproate ester, used in treatment of dysfunctional uterine bleeding and menstrual cycle abnormalities, and in the diagnosis of endogenous estrogen production; administered orally. I use a pharmacy called MDR who makes an progesterone in a different oil that is less viscous and more easy to inject. Fat and Oil Melt Point Temperatures. Hi all, not really sure where to post this to get the most views, but here goes! I had a terrible reaction to the progesterone in sesame oil my last FET cycle and my Dr is trying to call in a prescription for progesterone in ethyl oleate and I cannot find a pharmacy to fill it! I had a rash all over my back early on. Cottonseed oil is less likely to cause injection site pain. In Figure II the percentage of rats which returned to estrus (tested in groups of ten) is plotted against weeks and the symbols used are as follows: O - aqueous microcrystalline suspension of ester of particle size 3 to 1,0v as hereinbefore defined - - solution in sesame oil # - solution in ethyl oleate The plots. It could be in peanut, sesame, cotton, olive, and ethyl oleate. Mine is in sesame oil. This medicine is not approved for use in children. , surfactant solution in the absence of oil) peppermint oil and ethyl oleate) have been used as vehicle in oily injections [1]. Surely someone can still make the kind you've been using. Contact your doctor if you have any symptoms that may be due to the progesterone treatment. I truly feel your pain. However, it is used by compounding pharmacies as a vehicle for intramuscular drug delivery, in some cases to prepare the daily doses of progesterone in support of pregnancy. , Hisar(Haryana), India b Department of Pharmaceutical Sciences,M D University, Rohtak(Haryana), India oil vs extract One ingredient that’s commonly found in natural skin care is Olive oil. Studies which document the safe use of ethyl oleate in pregnancy for both the mother and the fetus have never been performed. Warning: Ethyl Oleate. The different oils used in the injections differ in amount of pain caused. My doc prescribed PIO. Postal Address 50 Kambathi Street N4 Industrial Gateway Park Willow Park Manor Ethyl Oleate USP, NF, Non-GMO, GRAS Certified. Then with our last cycle and this one, its really bad. Kosher and halal certifed. Hydroxy Progesterone Caproate 250 mg/ml. Bodybuilders often stack it with Testosterone for one of the most common and effective bulking cycles. I talked to my clinic and even switching to injections in the thighs or injecting a lesser amount did not help relieve the problems. (2007) used estradiol valerate, progesterone, made up in ethyl oleate with 10% benzyl alcohol, and a placebo of ethyl oleate with 10% benzyl alcohol. Progesterone injection, a progestin, is a sterile solution of progesterone in a Absorption: After intramuscular administration of 10 mg of progesterone in oil  I had the same issue with the sesame oil. You could have more side effects. Use our prescription price comparison tool to find the best prescription drug price for PROGESTERONE IN OIL in your area, then use our prescription discount . At least never having to do another PIO injection is one upside to never being able to carry again! If you are a patient with allergies we can produce Progesterone in various forms – sesame oil, olive oil, ethyl oleate, and 17-hydroxy. PharmaCompass the one-stop, pharmaceutical information platform accelerates generic drug development by sharing the list of inactive ingredients used to develop Progesterone marketed by Actavis Pharma, Inc. Highly viscous suspensions of bovine somatotropin, marketed to increase milk production in dairy cows, and a bovine growth hormone releasing factor analogue, used to release somatotropin from the cow’s pituitary gland, have been formulated in sesame oil and miglyol oil, respectively. 00 Progesterone Vag. After experiencing some complications with our normal PIO injections (sesame oil) we are giving ethyl oleate a try for this transfer cycle. 4, 17, 18 These viscous suspensions require a large 14- to 16-gauge needle for injection, whereas the preferred needle size for humans is ~25–27 gauge. The switched me from progesterone in sesame to progesterone in ethyl oleate and it went away in a few days. I used progesterone in sesame oil with my first surro pregnancy for 12 weeks, and everything was fine. grapeseed, sesame, or cottonseed oil? I like Ethyl Oleate, but Grapeseed is a close second Yes, it does have a green tint to it 02-11-2009, 07:42 AM #7. She drew it up with an 18gauge, then switched needles to a 25 gauge for my tush. This may be formulated in ethyl oleate, sesame oil, olive oil, peanut oil, or other liquids. We will compound any  Progesterone can be administered by an injection or suppository. Intramuscular progesterone preparations contain various types of oils, such as sesame, peanut or olive oil. 65 . Progesterone In Oil Shortage December 6, 2017 December 6, 2017 MommySquared I was fortunate to start this cycle with 2. the kind in sesame (which is the kind most docs prescribe first). In making high concentration gear with an MCT oil base, ample amounts of BA and BB must be used as MCT oil does not act as a natural solvent for the steroid raw powders the way ethyl oleate does. _____ Donor ID/ Name: Donor D. Fats that are solid at room temperature are already frozen and fats that are liquid at room temperature Self Emulsifying Drug Delivery System: A Tool in Solubility Enhancement of Poorly Soluble Drugs Kavita Sapraa*, Ashu Saprab, S K Singha, Saloni Kakkarb a Department of Pharmaceutical Sciences, G J University of Science & Tech. The cyclobutylcarboxylic ester prepared as a microcrystalline suspension in ethyl oleate had only approximately 40% of the activity of the aqueous suspension. Progesterone in sesame oil, brand name Progesterone Injection USP,  Find user ratings and reviews for Progesterone in Oil intramuscular on WebMD I used the progesterone in sesame oil for about 10 days until I had an allergic My doctor switched me to oleate ethyl based progesterone afterward and I  19 Aug 2016 Ethyl Oleate- This is a type of oil you may not be familiar with. We will compound any medication in a Lo Dose form as necessary to correctly fill your prescription. under NDC Code 0591-3128-79 containing the following excipients SESAME OIL(unii: QX10HYY4QV), BENZYL ALCOHOL(unii: LKG8494WBH) Progesterone in sesame oil, olive oil, ethyl oleate; progesterone suppositories; Crinone – I’ve been on it all and had plenty of the little disasters that accompany them. Valproic acid has been formulated as an oil solution but, other than that, oil solution dosage forms are primarily known from fat soluble vitamins; vitamin A, D and E are often dosed in oil. Then she took the syringe and put it in her elbow and bent her arm for a few minutes. Prop is also good as a taper off drug after a longer cycle with long esters such as Cyp or Enan. 184 NATIONAL HEALTH (PHARMACEUTICAL BENEFITS) REGULATIONS (AMENDMENT) - SCHEDULE 1 SCHEDULE 1 Sub-regulations 10 (1) and (2) DRUGS AND MEDICINAL PREPARATIONS IN THE BRITISH PHARMACOPOEIA THAT ARE NOT TO BE SUPPLIED AS OR, EXCEPT AS SPECIALLY PROVIDED, USED IN PHARMACEUTICAL BENEFITS 1 Acetarsol 2 Acetarsol Pessaries 3 Acetic Acid, Glacial 4 Acetone 5 Adrenaline Acid Tartrate 6 2. 83 Progesterone Vag. With suppositories the progesterone is delivered to the uterus and makes it harder to monitor in the blood. use 50ml eo and 50ml grapeseed oil. We routinely order progesterone in Ethyl Oleate at the 100 mg/1mL concentration. In my experience, the ethyl oleate is much kinder on the bottom than the sesame is. Find user ratings and reviews for Progesterone in Oil intramuscular on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction FAQ--Tell Me About PIO (Progesterone in Oil) This post is for the wiki, so if you have an answer to contribute to this topic, please do so. Progesterone. Cottonseed Oil Progesterone in Oil 50mg/ml ( 10ml Vials)( Refills) Inject ml(s) times a day Ethyl Oleate Olive Oil ( 10ml Vials)( Refills) Inject ml(s) times a day Use as directed up to # ml(s) Progesterone in Oil 100mg/ml Crinone® 8% Appl The Pharma grade Sesame oil complies the British Pharmacopeia monograph. Therefore, all injectable preparations made to date have been produced with oil-based solvents (usually peanut or sesame oil or ethyl oleate). Absorbed slowly and evenly by the body, this oil-based product sets the gold standard for progesterone support. By the time of the beta test (sadly negative) I had started developing hives at the injection sites. he said its easier to inject and you can use a smaller needle because it is not as thick as oil. Try to find a prop with less benzyl alcohol, more benzyl benzoate and better yet, ethyl oleate as the carrier vs sesame oil. Good luck! Is anyone else having to take the progesterone injections? There’s a national shortage of progesterone in oil so they have switched me to progesterone in ethyl oleate. • Progesterone Injection Cottonseed Oil 50 MG/ML • Progesterone Injection Olive Oil 50 MG/ML, 100 MG/ML • Progesterone Injection Sesame Oil 50 MG/ML, 100 MG/ML • Progesterone Injection Ethyl Oleate 50 MG/ML, 100 MG/ML • Hydroxy Progesterone Caproate 250 MG/ML • Compounded Leuprolide Acetate 1MG/. O. I had to use sesame oil for the last 3 cycles because it was all my insurance would cover and it was tough. 79 The solubility of the drugs Progesterone and . ) A low progesterone treatment usually consists of several cycles and involves a hormone therapy for improving the balance of estrogen and progesterone levels in women. progesterone(unii: 4g7ds2q64y) (progesterone - unii:4g7ds2q64y) progesterone: 50 mg in 1 ml Perhaps your supplier used ethyl oleate while their product happened to use, say, sesame oil. Fulvestrant is a particularly lipophilic molecule, even when compared with other Vidal Ethyl *40% 2ml < lweek enantate 1999 oleate Progesterone 50mg oil 0. another,  22 Oct 2013 Progesterone is available in sesame oil, cottonseed oil, olive oil and ethyl oleate. The PIO in ethyl oleate that I have gotten is compounded at 100mg/mL so in addition to being thinner the dosage was 1/2 as much as sesame. 90 for 1 vial $130. Progesterone in oil Progesterone in oil (50mg/ml) intramuscular injections will begin the day after the IVF egg retrieval or the day after the IUI. It is a colorless to light yellow liquid. Common side effects of progesterone injection include: Best Answer: It could be that you are allergic to the base the progesterone is in. I ended up going back to sesame oil. 2、40ml for 100mg/ml. A lot of people choose to go with ethyl oleate when they are delivering their progesterone and this is because it is less viscous and it also needs a much thinner needle as well so it can be less painful. Many of our surrogates tell us that sesame oil results in some of the most manageable While some patients report far less pain with one type of oil vs. Studies  30 Nov 2017 Olive oil is the thickest of the three, while ethyl oleate is the thinnest. Some liquids such as 2-pyrrolidone, tetra ethylene glycol, polyethylene glycol (PEG) and N-methyl pyrrolidone (NMP) have been claimed as biocompatible solvent for in-situ forming gel drug delivery system [2]. Progesterone – is a natural hormone produced by the ovaries. It is also seen in cottonseed oil, olive oil and more. This may be formulated in ethyl oleate, sesame oil, olive oil, peanut oil, or other  10 Jun 2003 oil), organic liquids/semi-solids (beeswax, d-α-tocopherol, oleic acid, medium- chain mono- and . A good kind of carrier oil for homebrew steroid injections should be thin,clean,sterile,painless,low in particulate matter,anallergic,and has good solubilizing ability. Caproate Injectable, Progesterone in Ethyl Oleate Injectable, and Progesterone in Sesame Oil Injectable drug products are labeled for injection and must meet the compendial standards for injectable products. * Compounded Leuprolide Acetate 1MG/. Progesterone suppositories; Progesterone lozenges, which are made to order by a pharmacist *Progesterone in oil can also come in a variety of carrier oils. I was given a full vial of P4 in sesame oil that was so thick drawing it took forever and it left knots at the site. , fibroids, cancer of the uterus). Sher Fertility Institute 146,825 views Ethyl oleate was the best oil for me. f, can be used as a measure of . is in an oil solution (sesame oil, cotton seed oil, and ethyl oleate are common carriers for the   12 Jun 2011 It's progesterone in oil and it's standard protocol for IVF. Luckily, sesame oil isn’t the only oil used to make the progesterone injection. 2ML Although testosterone propionate was readily soluble in the ethyl esters ethyl oleate, ethyl caprylate, and ethyl butyrate, and the triglycerides soybean oil, Miglyol 812, and tributryin, and the alkene 1-heptene, only microemulsions containing the ethyl esters and the triglyceride oils exhibited a significant increase in solubilization over the corresponding micellar solution (i. A few years ago I did progesterone in sesame oil and I got lumps and seemed allergic. 00 for 2 vials. 25ml ethyl Answers. the injection will be very smooth. Sesame Oil: Mid-level consistency for IM injection. Pain at the injection site is common. Further reduction in activity was observed when this compound was prepared as a solution in a 50:50 mixture of ethyl oleate and benzyl benzoate (BB). Drug Name of ingredient Comment References Diazepam S- tween 80 O- ethyl laurate,ettyl oleate Cos- propylene glycol, ethanol ME system be a promising approach for the -----corn oil, cottonseed oil, peanut oil, and sesame oil-Fixed oils are used as vehicles for certain hormone (e. Eur and USP and is derived by a process that uses advance refining method designed to provide a very high quality Sesame oil that is intended for use in the manufacture of parenteral preparations. The next shot is the PIO, or Progesterone In Oil. 06 Miglyol 812 2. Progesterone in Ethyl-Oleate: This injection is a form of progesterone mixed with Ethyl Oleate (for absorption). Good luck on finding a routine that helps to minimize the discomfort. There are a few types of progesterone that can be prescribed by the RE: Progesterone in oil, which is an intramuscular injection, commonly referred to as PIO* This "thick" oil is necessary to make the hormone progesterone injectable. I immediately get these itchy red welts around the whole injection area. 803726 Progesterone USP (Y5) Micronize 10 G 14K12-U03-021723 05/10/19 $ 10. progesterone in sesame oil vs ethyl oleate

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